Convenient premade gel with excellent stability even in low pH formulations (pH 2-7.It also can be compounded with a variety of APIs, such as hormones, alpha-hydroxy acids, hydroquinone, steroids, certain anesthetics and more. This base can be used in combination with PCCA Mucolox™ for patients with vaginal and rectal conditions that would benefit from enhanced mucosal adherence. It can also be used as a thickener or stabilizer for emulsions and can be diluted with up to 50% alcohol to easily create hydro-alcoholic topical gels, ideal for testosterone therapy in men. It is extremely stable and can be used topically, vaginally and rectally. VersaBase Gel is transparent, smooth and light to touch, with a silky feel that spreads and absorbs easily. Physicians who prescribe these drugs, as well as pharmacists who compound and dispense them, must assure that patients are provided with instructions about possible adverse effects, safe storage, and proper use.A stable gel base for various topical preparations With compounded pain creams and ointments, we are specifically concerned about some compounding company statements that may be unproven, such as the products' safe use with children.Ĭompounded pain creams need prominent warnings on labels that describe the potential for toxicity. Because safety issues can arise with any compounded, unapproved formulations of medications, regulatory or licensing oversight is necessary. The products, which are not packaged in containers with a safety closure, also may not be as carefully stored as other medications in order to avoid accidental child exposures. Patients may be unaware of potential dangers with these creams. Also, a 47 year old female experienced a low hear rate, slurred speech, and dizziness, after applying her compounded pain cream containing five ingredients, including clonidine, a blood pressure medication. In a case reported last year, severe toxicity occurred in an 18-month-old child when his father's compounded ointment was used to treat a diaper rash.
#Versapro cream ingredients skin
Pediatric patients have also experienced toxicity when the cream is applied to their skin intentionally for a skin condition. This cream, compounded along with 4 other ingredients, into a topical. In one case, a child who became severely ill after applying his mom's compounded topical fibromyalgia medication to his body-gabapentin, ketamine, diclofenac, clonidine, nifedipine, bupivacaine, menthol, and cyclobenzaprine. Find 3 user ratings and reviews for Versapro Cream Base Topical on WebMD including. It has been proven to deliver more drug transdermally than PLO gel. There have been cases of children ingesting or applying the creams, of adults intentionally abusing it, and of adults experiencing adverse effects with appropriate use. Lipoderm® cream is a transdermal base with a smooth consistency & is stable at room temperature & under refrigeration. Someone told me it was just aloe and vitamin E, but the cream is white, so I. The Philadelphia Poison Control Center, one of our nation's 57 Poison Control Centers, has had 8 cases reported as a result of these products in the last 12 months, and no cases prior to that. What are the ingredients in VersaPro cream base I couldn t find it listed anywhere when I searched for it on the internet. In fact safety is likely to be more of an issue, even when used by the intended patient at the intended site. Prospective patients are even receiving unsolicited calls at home, with a promise that the cream can be prescribed after an arranged telephone consultation with a physician.Ĭonsumers are charged per ingredient and there is really no proof that more ingredients make the product better. Their use is growing, prompting some pharmacies to employ a sales force, initiate elaborate marketing campaigns, and provide template prescriptions to make prescribing of these creams easier. Some compounding pharmacies are filling prescriptions for these pain creams for specific patients. Most of these drugs have not been US Food and Drug Administration (FDA)-approved for topical use (although off-label use of medications is routine). Many include drugs that can cause central nervous system depression or cardiac effects such as ketamine, baclofen, cyclobenzaprine, lidocaine, tricyclic antidepressants, gabapentin, clonidine, and nifedipine. Some compounding pharmacies are preparing compounded pain creams and ointments that contain a combination of multiple potent medications.